I do not think there will be any dramatic changes simply because this was already the direction the services, especially the USAF, were moving in. There already are programs like ETV, ERAM, MACE, etc and multi year weapons buys have been embraced as a cost saving measure for greater inventory (AMRAAM, JDAM, JASSM, etc). More over more and more private industry is starting to invest its own funds in producing products of this type and bringing them to market rather then waiting for programs of record (Ares, Anduril, GTS, etc).
So i doubt we see a single Manhattan project type effort or office and instead see continued incremental funding of new weapons and production lines, more expansion of existing lines, and more multi year buys of weapons to drive down costs. It will be a continuation of existing trends. If anything, Congressional funding is more relevant.