Side note: MOP and MOAB are not the same thing. MOP is the ~27,000lb GBU-57, MOAB is the ~22,000lb GBU-43. MOP only has about 5200lbs of explosive charge, while MOAB has over 18,000lbs of explosives and a yield of roughly 22,000lbs of TNT.
MOAB is also an air burst type.
I remember seeing some things like using reentry bodies as the penetrating warhead on missiles, but that was for something like ATACMS or maybe a newer missile that was roughly Polaris sized.
You don't want a conventional ballistic missile strike coming from an ICBM or SLBM location because it's going to look like a nuclear strike to anyone/everyone watching.