Covid-19 Vaccine - Where, How & Costs

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First time this variant has been detected in humans. There was no human to human transmission and there was no serious health consequences for the workers. Test & vaccine development will begin.

 
Seems the Pfizer BioNTech COVID-19 mRNA vaccine BNT 162b2 is the one in use for over 60yo here in Scotland (mother in law had her first jab this morning)
... Only issue, apart from queues at the surprisingly busy local vaccination centre, being the information leaflet re potential issues etc was handed to her after receiving the injection
 

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An interesting bit of kit...

Smiths Detection’s BioFlash shown to detect airborne COVID-19​

Smiths Detection revealed today that its BioFlash Biological Identifier is capable of detecting SARS-CoV-2 in the air following tests conducted by the United States Army Medical Research Institute of Infectious Diseases (USAMRIID).

The tests were performed using live SARS-CoV-2 virus in a Biosafety Level 3 containment area at Fort Detrick, Maryland. The SARS-CoV-2 CANARY biosensor used in the BioFlash device demonstrated that it can quickly detect and identify the presence of low levels of aerosolized SARS-CoV-2.

More at -

 
View: https://mobile.twitter.com/mdbuckley/status/1363823529901309952


It infuriates me why are these people not listening to their experts yet again. Oh sorry I forgot the economy. But this will lead to more economic damage as well as more deaths. Plus it could produce new variants which could undermine the progress of vaccination not just here but everywhere if they escape from the U.K.:mad:

Well, there are many different variants floating around already and unless covid is 100% wiped out they will continue to increase so if people are saying wait until there are no more variants, they could be in for a long wait.

There have been suggestions that lockdown have prevented version that are less dangerous from evolving.

....plus of course this years flu season is going to be worse than normal.
 
Interesting results coming in from the UK vaccinations that suggest that the AZ vaccine which is being rubbished by many is better at prevented hospitalisations than the Pfizer one 94% vs 85%.

 
Update on vaccination rate globally:

LocationTotal dosesDoses administeredper 100 peopleDays sincefirst dose
Gibraltar29,3348743
Israel7,357,8228565
Seychelles65,0606643
UAE5,554,3425653
Falkland Is.1,5154414
Guernsey19,2842967
Cayman Is.18,1592845
UK18,197,2692776
Jersey25,9522671
Bermuda13,1552142
Isle of Man17,4992149
USA63,090,6341970
Anguilla2,7621817
Turks + Caicos Is.6,4331742
Bahrain274,9601667
Chile2,891,1071560
Serbia987,0001560
Malta63,3081457
Maldives75,0131421
Faroe Is.5,6821254
Denmark485,201857
Turkey6,571,830840
Iceland25,718855
Romania1,379,224757
Poland2,715,159757
Switzerland611,842761
Slovenia144,075757
Lithuania188,164757
Norway371,630757
Hungary654,462758
Slovakia367,632758
Greece697,245749
Morocco2,461,192725
Estonia87,957757
Portugal675,453757
Ireland326,475755
Finland363,938757
Cyprus56,791657
Spain2,936,011657
Singapore360,000654
Monaco2,400653
Germany5,068,829658
Sweden585,843657
Italy3,503,767657
Belgium667,044656
Austria498,476657
France3,716,619557
Czech Rep.545,381557
Barbados14,411512
L'bourg28,933556
Netherlands779,889547
Greenland2,584549
Kuwait175,000460
Liechtenstein1,504435
Canada1,402,139470
Qatar100,000361
Croatia142,222357
Brazil6,950,802336
N. Cyprus11,000338
Mainland China40,520,000369
Andorra2,141333
Russia3,900,000379
Latvia44,844256
Costa Rica96,948260
St. Helena, Ascension + Tristan da Cunha107227
Bulgaria119,354257
Argentina720,267255
Sri Lanka338,769224
Saudi Arabia501,710167
Mexico1,689,158160
Oman64,538157
Bangladesh2,082,877115
Panama47,848133
India11,085,173< 137
Indonesia1,956,725< 140
Azerbaijan65,000< 135
Nepal158,487< 126
Peru166,090< 113
Macao2,000< 113
Mauritius3,843< 127
Belarus20,944< 155
Myanmar103,142< 126
Lebanon12,718< 18
Algeria75,000< 123
Albania4,177< 142
Bolivia10,167< 124
Guyana668< 111
Colombia39,827< 15
Ecuador8,190< 132
S. Africa15,388< 15
Pakistan72,882< 120
Cambodia4,609< 112
Iran10,000< 113
New Zealand100< 12
Japan5,039< 15
Egypt1,315< 129
Dom. Rep.373< 16
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  • Last updated: February 23, 2021 at 5:03 a.m. ET
 
The thing to remember is that all viruses mutate. That is why, in the US, there is a new flu vaccine every year. This particular virus has mutated within that time. The response to the variants shows a much quicker reaction time. As the US passes 64.2 million vaccinations, various venues are opening back up and the pace of reopenings should increase rapidly.
 
A nightmare inside a nightmare?!!

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Now, the vision is to harness more generalised responders, known as broadly neutralising antibodies. These types of antibodies have been isolated from Covid-19 patients and found to also neutralise Sars-Cov-1, another virus in the coronavirus family responsible for severe acute respiratory syndrome, or Sars. If they can quash several distinct coronaviruses, then they might also be able to combat current and future variants of the pandemic virus.

The challenge comes in finding a jab that produces these versatile antibodies. One starting point is to identify which parts of the virus remain unchanged as it mutates and then designing vaccines on the basis of these stable regions.

Researchers at the University of Nottingham in the UK are adopting this approach. While current vaccines target the S (spike) protein, they are gunning for both the S protein and the nucleocapsid, or N, protein. The latter helps the virus to replicate and mutates more slowly than the spike protein. The scientists have teamed up with the company Scancell and Nottingham Trent University for a phase 1 clinical trial of its vaccine candidate, SN14.

The current jabs might also offer clues, according to Deborah Dunn-Walters, professor of immunology at the University of Surrey and chair of a Covid-19 task force. “We will eventually have lots of different vaccines and some might be more tolerant of variants than others,” she says. Those, she suggests, could be iterations along the road to a universal vaccine.

 
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Viral vector vaccines may fall by the wayside if repeat shots are needed as the immune system may start attacking and destroying the vector itself if they become overly familiar with it.

 
Among those that have managed to trick the system to cut waiting lines for vaccination, there is now an ex head of state, the 66 years old French president Sarkozy (report in Fr):

Screw him. The only consolation is - he must have taken only half a dose, considering how small Sarkozy is. You could even put him in your pocket (except it would eat your tight with his pointy teeth, so better not do that).

:p :p
 
Here’s a more scientific and level headed article on the California COVID variant.


Related paper:

 
Beyond the moral argument, there are sound economic and public health reasons to close the gap. Vaccinating those most at risk around the world would drive down hospitalizations and deaths everywhere sooner, allowing societies to reopen and economies to recover. It could also help reduce circulation of the virus globally, lowering the risk of new virus variants emerging.

 
A sobering article on when you can expect to return to normal, the first answer is what do you call normal, the second answer in spite of what politicians will have you believe is no one can really say at this time. Also that this idea of herd immunity is just pie-in-the-sky thinking. Furthermore though vaccines stop deaths and hospitalisation they do little to tackle lower level infections at which point the virus can still evolve more dangerous variants. Vaccines put the virus on a leash but they don’t stop it getting off the leash or biting you in the leg.

 


 
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