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As an aeronautical engineer who majored in aerodynamics and minored in propulsion, this is complete nonsense. We have good ideas based on our known calculations regarding how the aircraft will behave in the static domain and to a certain extant in the dynamic domain as well. Where you run into trouble is when the airflow is mainly non-steady, such as at high alpha with massive amounts of flow separation. That's where tools such as CFD, the wind tunnel, and of course, best of all, actual flight testing, come into play.